Humanin 10mg (CAS 330936-69-1) is a high-purity neuroprotective mitochondrial peptide API, produced under strict GMP standards to ensure ≥98% purity (HPLC). As a 24-amino acid peptide encoded by mitochondrial DNA, it offers multifaceted cytoprotective effects, particularly notable for its neuroprotective activity against Alzheimer’s disease-related insults.
The peptide acts by inhibiting Bax-mediated apoptosis, preventing Bax translocation from cytosol to mitochondria and blocking its conformational activation. This mechanism safeguards neurons from amyloid-β toxicity, mutant presenilin-induced damage, and various oxidative stressors. Beyond neuroprotection, Humanin demonstrates cardioprotective, hepatoprotective, and anti-diabetic properties in preclinical models, making it a versatile research tool for age-related disease studies.
Ideal for pharmaceutical R&D, academic research, and biotech development, this water-soluble API supports investigations into neurodegenerative disorders, mitochondrial dysfunction, and cellular stress response. Its natural origin and well-documented cytoprotective profile position it as a valuable raw material for developing novel therapeutic approaches targeting age-related conditions.
