Alprostadil (CAS 745-65-3) – Vasodilator API

Alprostadil (CAS 745-65-3) is a high-purity prostaglandin E1 (PGE1) vasodilator API, with a natural molecular structure that exerts potent vasorelaxant and antiplatelet effects. Its core mechanism activates adenylate cyclase in vascular smooth muscle cells, increasing cyclic adenosine monophosphate (cAMP) levels to relax blood vessels, improve blood flow, and prevent platelet aggregation. Produced under strict GMP-compliant processes, it ensures ultra-high purity, consistent bioactivity, and compliance with international cardiovascular and urological pharmaceutical standards.

This premium API is a core raw material for pharmaceutical manufacturers developing treatments for erectile dysfunction and peripheral vascular diseases. It is widely applied in formulating injectable or topical medications for erectile dysfunction, as well as therapies for critical limb ischemia and Raynaud’s phenomenon. With proven clinical efficacy and targeted action, it addresses the critical demand for safe vasodilator solutions in urology and cardiovascular care. For R&D teams and production enterprises, it provides a trusted solution to advance vascular health and sexual medicine drug development.