Amlodipine Besylate (CAS 111470-99-6)-Amlodipine Besylate Powder 

Amlodipine Besylate (CAS 111470-99-6) is a high-purity pharmaceutical API classified as a potent calcium channel blocker, featuring a dihydropyridine molecular structure with selective activity on vascular smooth muscle. It exerts antihypertensive and antianginal effects by inhibiting calcium ion influx into vascular smooth muscle cells and cardiac myocytes, relaxing peripheral and coronary arteries to lower blood pressure and improve myocardial perfusion. Unlike short-acting alternatives, it has a long half-life (24 hours), enabling once-daily administration for sustained efficacy.

Presented as a white to pale yellow crystalline powder with excellent solubility and stability, it is easy to formulate into oral dosage forms. It caters to the core needs of cardiovascular drug manufacturers, antihypertensive formulation developers, and clinical supply chains. Widely applied in treating hypertension, chronic stable angina, and vasospastic angina, it aligns with demand for well-tolerated, long-acting cardiovascular therapies. Produced under strict GMP standards, each batch undergoes rigorous purity, dissolution rate, and potency testing to meet international pharmacopoeia requirements, ensuring consistency for clinical use.