Faropenem (CAS 122547-49-3)/ Antibacterial

Faropenem (CAS 122547-49-3) is a high-purity pharmaceutical API classified as a potent carbapenem antibiotic, featuring a tricyclic carbapenem molecular structure with broad-spectrum antibacterial activity. It exerts bactericidal effects by inhibiting bacterial cell wall synthesis—binding to penicillin-binding proteins (PBPs) to block peptidoglycan cross-linking, leading to cell lysis. Unlike other carbapenems, it offers excellent oral bioavailability and stability against renal dehydropeptidase I (DHP-I), eliminating the need for a DHP-I inhibitor co-administration.

Presented as a white to off-white crystalline powder with good solubility, it is suitable for oral dosage forms. It caters to the core needs of antibacterial drug manufacturers, infectious disease therapy developers, and pharmaceutical formulators. Widely applied in treating respiratory tract infections, urinary tract infections, and skin/soft tissue infections caused by Gram-positive and Gram-negative bacteria (including drug-resistant strains), it aligns with demand for convenient, broad-spectrum antibacterial solutions. Produced under strict GMP standards, each batch undergoes rigorous purity, antimicrobial activity, and stability testing to meet international pharmacopoeia requirements, ensuring consistency for clinical use.