Ipilimumab (CAS 477202-00-9) – Anti-CTLA-4 Monoclonal Antibody Anticancer API

Was $210 Now $190
Sale
  • Ipilimumab (CAS 477202-00-9) is a high-purity pharmaceutical API classified as a CTLA-4 inhibitor, featuring a recombinant fully human IgG1 kappa monoclonal antibody structure with a molecular weight of approximately 148 kDa. It specifically binds to cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), blocking its interaction with CD80/CD86 ligands to release T-cell inhibition—activating anti-tumor immune responses and forming long-lasting immune memory. This premium API exhibits strong target affinity and stable bioactivity, ensuring consistent performance in injectable formulations.

  • It caters to the core needs of oncology drug manufacturers, biotech firms, and clinical research institutions. As a pioneering immune checkpoint inhibitor, it is widely applied in developing treatments for unresectable or metastatic melanoma, renal cell carcinoma, and malignant pleural mesothelioma. Produced under strict GMP-compliant biomanufacturing processes, each batch undergoes rigorous purity and potency testing to meet global biopharmaceutical standards. For businesses focusing on innovative immunotherapies, this Ipilimumab API serves as a critical raw material for advancing targeted anticancer therapy research and clinical applications.