Pimobendan (CAS 74150-27-9) -pimobendan api powder

Pimobendan (CAS 74150-27-9) is a high-purity pharmaceutical API classified as a potent cardiac inodilator, featuring a benzimidazole-pyridazinone molecular structure that exerts dual mechanisms of action. It acts as a selective phosphodiesterase III (PDE III) inhibitor to enhance myocardial contractility (positive inotropy) and a calcium sensitizer to improve cardiac efficiency without increasing oxygen demand—while dilating systemic and pulmonary vasculatures to reduce cardiac workload. This unique combination makes it superior to single-action heart failure therapies.

It caters to the core needs of cardiovascular drug manufacturers, veterinary pharmaceutical developers, and clinical supply chains. Widely applied in treating congestive heart failure (CHF) in humans and companion animals (dogs, cats), it aligns with demand for effective, well-tolerated cardiac support therapies. Produced under strict GMP standards, each batch undergoes rigorous purity and potency testing to meet international pharmacopoeia requirements, ensuring consistency for clinical and veterinary use. For businesses prioritizing dual-action cardiac therapeutics, this Pimobendan API serves as a critical raw material for advancing heart failure medication development.