Tideglusib (CAS 865854-05-3)/Tideglusib Powder

Tideglusib (CAS 865854-05-3) is a high-purity GSK-3 inhibitor API with a targeted kinase-suppressing mechanism. As a potent and selective inhibitor of glycogen synthase kinase 3 (GSK-3α/β), it modulates key cellular signaling pathways involved in neuroprotection, inflammation, and cell survival. Its refined crystalline form ensures consistent bioactivity and ultra-low impurity levels, making it a reliable tool for pharmaceutical R&D.

This API is widely used in preclinical studies on neurodegenerative disorders such as Alzheimer’s disease and spinal muscular atrophy. It exerts neuroprotective effects by reducing abnormal tau phosphorylation and promoting neuronal survival, while also regulating inflammatory responses. For pharmaceutical manufacturers and neuroscience research institutions, its stable chemical structure and high selectivity offer flexibility in formulation design for preclinical trials and target validation studies.